Sept 29

John S. Cidlowski, PhD, National Institutes of Health – Section Chief, Laboratory of Signal Transduction Molecular Endocrinology Group

“Mechanisms Generating Diversity of Glucocorticoid Receptor Actions in Health and Disease”

Host: Richard A. Anderson

Oct 6

Lianwang Guo, PhD, Senior Scientist, Department of Pharmacology, University of Wisconsin-Madison, School of Medicine and Public Health

“The cGMP Phosphodiesterase g Subunit – A Critical Regulator of Visual Signal Transduction”

Host: Arnold E. Ruoho

Oct 13

Paul Insel, MD, Professor of Pharmacology and Medicine, Director of the Medical Scientist Training Program, University of California-San Diego

“Cyclic AMP: New Discoveries and Therapeutic Implications for an “Old” Second Messenger”

Host: Arnold E. Ruoho  

Oct 20

Jay H. Chung, MD, Principal Investigator, Lab of Biochemical Genetics, National Institutes of Health, National Heart, Lung and Blood Institute

“The Role of DNA-PKcs in Aging-Associated Decline in Mitochondrial Function: Implications for Obesity and Type 2 Diabetes”

Host: Randal S. Tibbetts

Oct 27

David Pagliarini, PhD, Assistant Professor, Department of Biochemistry, University of Wisconsin-Madison, College of Agricultural and Life Sciences

“Mitochondrial Proteomics and Pathogenesis”

Host: David A. Wassarman

Nov 3

William L. Murphy, Assistant Professor, Department of Biomedical Engineering, University of Wisconsin-Madison, School of Medicine and Public Health

“Biomaterials that Regulate Stem Cell Phenotype”

Host: Beth A. Weaver (Patti Keely will introduce.)

Nov 10

Brian Wadzinski, PhD, Associate Professor, Department of Pharmacology, Vanderbilt University, Vanderbilt Brain Institute

“Regulation of Cellular Signal Transduction Pathways by Protein Kinase/Protein Phosphatase 2A (PP2A) Signaling Modules”

Host: Arnold E. Ruoho

Nov 17

Zena Werb, PhD, Professor and Vice-Chair, Department of Anatomy, University of California-San Francisco

“Of Mice and Women: New Insights in Mammary Development and Breast Cancer”

Host: Beth A. Weaver

Jack Keene, James B. Duke Professor, Duke University

Coordination of gene expression by RNA-binding proteins and small RNAs

February 10

Dr. Mike Schwartz, University of Colorado-Boulder Howard Hughes Medical Institute Postdoctoral Associate

Synthetic extracellular matrix: A new tool for studying complex biological processes through the design of highly controlled 3-dimensional microenvironments

Hosts:  R. Tibbetts/Kevin Eliceri

February 24

Dr. Tracy Vargo-Gogola

P190-B RhoGAP regulates the microenvironmental during mammary gland development and cancer progression

Host:  P. Keely

Dr. Andrew Ulijasz, Postdoctoral Fellow, UW-Madison, Genetics Dept.

Prokaryotic and Eukaryotic-like Signal Transduction Merge to Regulate Virulence in Streptococcus pneumoniae

Host: Tibberts or Weisblum

March 24

Randal Tibbetts, Professor, Department of Pharmacology, School of Medicine and Public Health, University of Wisconsin-Madison      

Dr. Crislyn D’Souza-Schorey, PhD, Associate Professor, University of Notre Dame, Dept. of Biological Sciences

Modeling epithelial morphogenesis and tumor cell invasion

Host:  R. Anderson

Dr. George Q. Daley, PhD, Professor, Harvard Medical School and Howard Hughes Medical Institute  

Prospects for Cell Therapies From iPS Cells

Host:  D. Mosher

April 21

Microbial Sciences Building, 1550 Linden Drive

Dr. Tsung-Ping Su, PhD – NIH, National Institutes on Drug Abuse

ER Stress Signaling and Chaperons in Diseases:  A new kid on the block

Host: A. Ruoho

Dr. Ryo Sakasai, Research Associate, Pharmacology Dept., UW-Madison 

From R. Tibbetts lab

Scott Soderling, PhD, Duke University Medical Center, Department of Cell Biology

Spatial Regulation of Rho GTPase Activating Proteins

Host: R. Anderson

Mark Burkard, Assistant Professor, Department of Medicine/Hematology-Oncology, School of Medicine and Public Health, University of Wisconsin-Madison

Host: R. Tibbetts

Dr. Randy Blakely, PhD, Allan D. Bass Professor of Pharmacology, Vanderbilt University 

Dopamine in Flux: Insights into Attention Deficit Disorder from Rare Mutations in Dopamine Transporters

Host:  R. Ruoho

Paul Brindle, PhD, Associate Member, Department of Biochemistry, St. Jude Children's Research Hospital
What's up with histone acetylation and transcription in mammals?

Nissim Hay, PhD, Professor, Department of Biochemistry and Molecular Genetics, The University of Illinois at Chicago The role of Akt (PKB) in energy metabolism and the genesis of cancer

Peter Jackson, Director, Staff Scientist: Cell Regulation, Genentech
How Microtubules, Vesicles, Acetylation, and Signaling Pathways Direct Formation of the Primary Cilium

Sergio Grinstein, PhD, Professor, Division of Cell Biology, The Hospital for Sick Children
Signaling phagocytosis: role of phospholipids and surface charge

Kevin Eliceiri, Department of Molecular Biology, University of Wisconsin-Madison
Computational and Optical Approaches to Multidimensional Live Cell Imaging

Jo Handlesman, PhD, Professor, Departments of Bacteriology and Plant Pathology, University of Wisconsin-Madison
TBA

Rogers Hollingsworth, PhD, Professor, Department of History, University of Wisconsin-Madison
Perspective on Contemporary American Science in the Context of the Rise and   Decline of Hegemonic Systems of Science

James Bear, PhD, Assistant Professor, Department of Cell and Developmental Biology, UNC-Chapel Hill
Coronins: ancient regulators of protrusion and adhesion

Jan Van Deursen, PhD, Professor, Departments of Oncology and Pediatrics, Mayo Clinic 
The mitotic checkpoint in cancer and aging

Crislyn D'Souza-Schorey, PhD, Associate Professor, Department of Biological Sciences, University of Notre Dame
Modeling epithelial morphogenesis and tumor cell invasion

Harry Orr, PhD, Professor, Department of Laboratory Medicine and Pathology, University of Minnesota
Molecular and Neuronal Alterations in a Polyglutamine Neurodegenerative Disease - The SCA1 Story