Aude S. (Ada-Nguema) Peden, PhD

Graduation: 07/2005
Advisor: Keely, Patricia
Current Position: J.D. Student
Boston University School of Law
Expected graduation: May 2018
Research Interest: Genetic Characterization of Phospholipase C-beta role in the control of Rhythmic Behaviors in C. elegans.
Email: apeden (at) utk (dot) edu

Alumni News

  • From Aude S. Ada-Nguema (Peden) on her current work:
    • “I started with ‘Genetic Characterization of Phospholipase C-beta role in the control of Rhythmic Behaviors inC. elegans’. This work led me to identify a trimethylglycine (betaine)-signaling pathway in the nematode that is involved in sensorimotor integration of locomotory behavior. I isolated both the betaine transporter and the betaine receptor. I have been trying to define the betaine neuronal circuit in the worm. It is a long a tedious process because no one has ever shown that betaine was a neuromodulator before. I have to make my own path with this project.”

Publications

  • Conklin MW, Ada-Nguema A, Parsons M, Riching KM, Keely PJ (2010). R-Ras regulates beta1-integrin trafficking via effects on membrane ruffling and endocytosis. BMC Cell Biol. 11:14. PMCID: PMC 2830936
  • Provenzano PP, Eliceiri KW, Yan L, Ada-Nguema A, Conklin MW, Inman DR, and Keely PJ. (2008) Nonlinear optical imaging of cellular processes in breast cancer. Microsc Microanal. 14:532-548. PMID: 18986607
  • Conklin MW, Ada-Nguema A, Parsons M, Riching KM, and Keely PJ. (2010) R-Ras regulates beta1-integrin trafficking via effects on membrane ruffling and endocytosis. BMC Cell Biol. 11:14. PMID: 20167113
  • Ada-Nguema AS, Xenia H, Sheetz MP, and Keely PJ. (2006). The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLCe. J Cell Sci. 119:1307-1319. PDF PMID: 16537651
  • Woller MJ, Meyer S, Ada-Nguema A, Waechter-Brulla D. (2004). Dissecting autocrine effects on pulsatile release of gonadotropin-releasing hormone in cultured rat hypothalamic tissue.  Exp Biol Med. 229:56-64. PDF PMID: 14709777
  • Woller M, Tessmer S, Neff D, Nguema AA, Roo BV, and Waechter-Brulla D. (2001). Leptin stimulates gonadotropin releasing hormone release from cultured intact hemihypothalami and enzymatically dispersed neurons. Exp Biol Med.226:591-596. PDF PMID: 11395931