UNIVERSITY OF WISCONSIN-MADISON
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MOLECULAR AND CELLULAR PHARMACOLOGY GRADUATE TRAINING PROGRAM Search: 
Miyamoto

Faculty: Shigeki Miyamoto, PhD

Dept: Professor, Oncology
Contact: 6159 WIMR
608-262-9281
smiyamot@wisc.edu
Training Areas:
  • Molecular and Cellular Pharmacology
  • Cellular & Molecular Biology
  • Molecular Biosciences
  • Cancer Biology
  • MD/PhD Program
  • Hematology Training Program

Research Interests

Our laboratory studies regulation of the transcription factor NF-kB as a model system to learn how normal growth control and cell death are regulated and how deregulation of such processes may contribute to development of cancer. NF-kB is normally sequestered in the cytoplasm by an inhibitor protein, IkB. A variety of extracellular signals induce rapid release of IkB from NF-kB, thereby allowing nuclear translocation of NF-kB to activate target gene expression. The products of these NF-kB target genes regulate diverse biological processes, including immune function, growth control and apoptosis. We are currently investigating the following three specific areas of research:

Honors & Awards

Selected Publications

(Find further publications on PubMed)