2001 Signal Transduction Research Training Symposium

October 2, 2001 : Fluno Center, Madison, WI

Sponsors: Molecular and Cellular Pharmacology Training Program, the UW Comprehensive Cancer Center, the Department of Pharmacology and the Molecular Biosciences Training Program and Progmega Corporation.

Symposium Committee: Patricia J. Keely (Chair), Richard Burgess, Alan Rapraeger, David Wassarman, Katarzyna Modzelewska, Lynn Squire.

Acknowledgements: UW Comprehensive Cancer Center, Molecular Biosciences Training Grant, Department of Pharmacology, Molecular and Cellular Pharmacology Program, Promega Corporation.

Symposium Agenda

8:00-8:30 Continental Breakfast – Registration if Necessary

8:30 Richard Anderson – Introduction
Director, Molecular and Cellular Pharmacology Program

8:45 Dean Paul DeLuca – Welcome
University of Wisconsin Medical School

Patricia Keely – Chair – Symposium Committee

Chair: Dr. Arnold Ruoho

9:00-9:20 Bacterial RNA Polymerase as a Target for Drug Discovery
Veit Bergendahl
Department of Oncology

9:25-9:45 Tissue Specific Heparan Sulfates Regulate FGF Signaling
Ben Allen
Department of Human Cancer Biology

9:50-10:10 Agonists & Antagonists: Different Functions & Binding Domains
Jessica Holden
Molecular and Cellular Pharmacology Program

10:15-10:35 Environmental Database for Gene Expression
Kevin Hayes
Molecular and Cellular Pharmacology Program

10:40-11:00 Inhibitors of p53 and DM2 Protein-Protein Interactions
Stephen Knight
Molecular and Cellular Pharmacology Program

11:00-12:00 Poster Session and Coffee Break

12:00 -1:00 Signaling from Adhesions to Rho GTPases
Dr. Keith Burridge
University of North Carolina

1:00- 2:00 Lunch

Chair – Dr. Deane Mosher

2:00-2:20 Overexpression of Syndecan-1 Extracellular Domain
Brandon Burbach
Molecular and Cellular Pharmacology Program

2:25-2:45 Interaction Between Pyk2 and NMDA Receptor Complex
Gail Seabold
Molecular and Cellular Pharmacology Program

2:50-3:10 Calpain Regulation of Focal Adhesion Dynamics and Turnover
Amit Bhatt
Molecular and Cellular Pharmacology

3:15-3:35 PIPKIa Regulation of Actin Cytoskeleton
Renee Dierckman
Molecular and Cellular Pharmacology

3:40-4:00 Cdc42-Induced Integrin-mediated Cell Migration
Katarzyna Modzelewska
Molecular and Cellular Pharmacology

4:00-5:00 Poster Session and Coffee Break

5:00-5:45 Tutorial on DNA Microarrays
Dr. Jeremy Glasner
Laboratory of Dr. Fred Blattner – Genetics

5:45 Reception