Dr. Tim Bugni Collaboration with Dr. Currie on New Source of Antibiotics

UW-Madison Scientists have discovered a new antibiotic from a Brazilian fungus-farming ant, naming it cyphomycin. Cyphomycin was effective in lab tests against fungi resistant to most other antibiotics and combatted fungal infections without causing toxic side effects in a mouse model.

School of Pharmacy Professor and MCP Trainer, Dr. Tim Bugni collaborated with Dr. Cameron Currie and other scientists to purify cyphomycin and determine its chemical structure. Cyphomycin was able to treat infection in mice by Candida albicans, an opportunistic fungal pathogen that often infects immunocompromised people. Cyphomycin also showed low toxicity in mice.

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