Matthew E. Brown, PhD
Position title: Assistant Professor, Department of Surgery; Director, UW Humanized Mouse Core Service
600 Highland Avenue
Madison, WI 53792
The Brown Lab focuses on exploring the nexus of pluripotent stem cell (PSC) biology and immunology. We are currently investigating the mechanisms underpinning the immune response to autologous and allogeneic PSC-derived cell therapies. Using transplantation immunology and genomics-based strategies, in conjunction with humanized mouse models, our goals are to 1) improve traditional organ transplantation outcomes, 2) gain new insights into PSC biology and immunology, and 3) enable curative regenerative medicine therapies.