Renee Doughman, PhD

Position title: Director - Human Research Oversight/IRB, Cincinnati Children's Hospital Medical Center


Phone: Advisor: Dr. Richard Anderson

Graduation: 08/2003
Research Interest: Functional diversity and local PI45P2 synthesis define phosphatidylinositol phosphate kinases

Renee Doughman


  • Dubash AD, Menold MM, Samson T, Boulter E, García-Mata R, Doughman R, and Burridge K (2009) Chapter 1. Focal adhesions: new angles on an old structure. Int Rev Cell Mol Biol. 277:1-65. Review. PMID: 19766966
  • Burridge K and Doughman R (2006). Front and back by Rho and Rac. Nat Cell Biol. 8:781-782. PDF PMID 16880807
  • Ling K, Doughman R, Iyer VV, Firestone AJ, Bairstow SF, Mosher DF, Shaler MD, and Anderson RA (2003). Tyrosine phosphorylation of type-1a phosphatidylinositol phosphate inase by Src regulates an integrin-talin switch. J Cell Biol. 163:1339-1349. PDF PMCID:PMC2173703
  • Doughman R, Firestone A, and Anderson RA (2003). Phosphatidylinositol phosphate kinases puts PIP2 in its place. J Memb Biol. 194:77-89. PDF PMID 14502432
  • Doughman R, Firestone A, Bunce MW, Wojtasiak M, and Anderson RA (2003).Membrane ruffle formation requires coordination of Type Ia phospha-tidylinositol phosphate kinase and Rac signaling. J Biol Chem. 278:23036-23045. PDFPMID 12682053
  • Coppolino MG, Dierckman R, Loijens J, Collins R, Persaud M, Jangstra-Bilan, Trimble WS, Schreiben AD, Anderson RA, and Grinstein S (2002). Indibition of Type 1 alpha phosphatidylinositiel – phosphate kinase impares localized actin remodeling – suppresses phagocytosis. J Biol Chem. 277:43849-4385. PDFPMID 12223494
  • Doughman R, Ling K, Firestone A, Bunce MW, and Anderson RA (2002). Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions. Nature. 420:89-93. PDF PMID 12422220
  • Botelho RJ, Teruel M, Dierckman R, Anderson R, Wells A, York JD, Meyer T, and Grinstein S (2001). Localized biphasic changes in phosphatidylinositol – 4, 5-bisphosphate at sites of phagocitosis. J Cell Biol. 151:1353-1367. PDF PMID 11134066