University of Wisconsin–Madison

Tyler Duellman, Phd

Development Scientist, HLA (Human Leukocyte Antigen) Lab, Department of Pathology and Laboratory Medicine, UW Hospital and Clinics

tduellman@wisc.edu

Advisor: Dr. Jay Yang

Graduation: 08/2014
Research Interest: Understanding the role genetic variation plays in altering gene regulation

Tyler Duellman

Alumni News

  • Tyler is currently a development scientist in the HLA lab (which tests for compatibility between donors and recipients for organ donation) at UW Hospital and Clinics. He is responsible for most of the technology and instrument validation that comes into the lab and is beginning to initiate some clinical studies.

Publications

  • Chu U*, Duellman T*, Weaver S, Yang J. (2015), Dissecting statin-mediated signaling leading to myopathy versus endothelial
    protection. Biochimica et Biophysica Acta, General Subjects, in submission.
  • Duellman T, Burnett J. Yang J. (2015) Functional roles on individual N-linked glycosylation sites within matrix metalloproteinase-9. Traffic, in submission.
  • Duellman T, Burnett J, Yang J. (2015). The lectin carrier protein, ERGIC-53, allows efficient MMP-9 secretion. Journal of Cell Science, in preparation
  • Schomberg D, Miranpuri G, Duellman T, Crowell A, Vemuganti R, Resnick D. (2015) Spinal cord induced neuropathic pain: molecular
    targets and therapeutic approaches. Metabolic Brain Disease, Epub ahead of print.
  • Kim HT, Uchimoto K, Duellman T, Yang J. (2015) Automated assessment of spontaneous pain in rats using a modified static weight-bearing test. Neuroscience Methods, in submission.
  • Duellman T, Warren C. Yang J. (2015) Transcriptional activation of multiple TIMPs utilizing CRISPR:Cas9. in preparation.
  • Duellman T, Warren C. Yang J. (2015) Genome-wide bioinformatics analysis of alterations in microRNA affinity. in preparation.
  • Duellman T, Warren C, Yang J. (2014) Single nucleotide polymorphism-specific regulation of matrix metalloproteinase-9 by multiple miRNAs targeting the coding exon. Nucleic Acids Research. 42(9): 5518-31.
  • Duellman T, Warren C, Matsumura J, Yang J. (2014) Analysis of multiple genetic polymorphisms in aggressive- and slow-growing abdominal aortic aneurysms. Journal of Vascular Surgery. 60(3): 613-621.
  • Duellman T, Burnett J, Yang J. (2014) Quantitation of secreted proteins using mCherry fusion constructs and a fluorescent microplate reader. Analytical Biochemistry, Epub ahead of print.
  • Duellman T, Warren C, Peissig P, Wynn M, Yang J. (2012) Matrix metalloproteinase-9 genotype as a potential genetic marker for abdominal aortic aneurysm. Circulation: Cardiovascular Genetics. 5(5): 529-37.
  • Rieger MA, Duellman T, Hooper C, Ameka M, Bakowska JC, Cuevas BD. (2012) The MEKK1 SWIM domain is a novel substrate receptor for c-Jun ubiquitylation. Biochem. J. 445(3): 431-9.