Molecular and Cellular Pharmacology Training Program
University of Wisconsin School of Medicine and Public Health

Michael Hanna, PhD

Position title: Postdoc, Pietro De Camilli Lab, Yale University

Email: michael.hanna@yale.edu

Phone: Advisor: Dr. Anjon Audhya

Address:
Graduation: 07/2017
Research Interest: Vesicular trafficking from the ER: mechanisms of the C. Elegans Coat protein complex II (COPII) at ER-exit sites and tfg-1

Mike Hanna

Publications

  • Hanna M, Wang L, and Audhya A., 2013, “Worming our way in and out of the Caenorhabditis elegans germline and developing embryo,” Traffic, 14:471-8. PMCID: PMC3622759
  • Shen QT, Schuh AL, Zheng Y, Quinney K, Wang L, Hanna M, Mitchell JC, Otegui MS, Ahlquist P, Cui Q, Audhya A, 2014, “Structural analysis and modeling reveals new mechanisms governing ESCRT-III spiral filament assembly,” J Cell Bio. 206(6):763-77. PMCID: PMC4164947
  • Johnson A, Bhattacharya N, Hanna M, Pennington JG, Schuh AL, Wang L, Otegui MS, Stagg SM, Audhya A, 2015, “TFG clusters COPII-coated transport carriers and promotes early secretory pathway organization,” EMBO J. 34(6):811-27. PMCID: PMC4369316
  • Schuh AL, Hanna M, Quinney K, Wang L, Sarkeshik A, Yates JR 3rd, Audhya A, 2015, “The VPS-20 subunit of the endosomal sorting complex ESCRT-III exhibits an open conformation in the absence of upstream activation,” Biochem J., 466(3):625-37. PMCID: PMC438465
  • Hanna MG 4th, Mela I, Wang L, Henderson RM, Chapman ER, Edwardson JM, Audhya. Sar1 GTPase Activity Is Regulated by Membrane Curvature. J Biol Chem. 2016 Jan15;291(3):1014-27. doi: 10.1074/jbc.M115.672287. Epub 2015 Nov 6. PubMed PMID:26546679; PubMed Central PMCID: PMC4714187.
  • Wang L, Johnson A, Hanna M, Audhya A. Eps15 membrane-binding and -bendingactivity acts redundantly with Fcho1 during clathrin-mediated endocytosis. MolBiol Cell. 2016 Sep 1;27(17):2675-87. doi: 10.1091/mbc.E16-03-0151. Epub 2016 Jul6. PubMed PMID: 27385343; PubMed Central PMCID: PMC5007088.
  • Hanna MG 4th, Block S, Frankel EB, Hou F, Johnson A, Yuan L, Knight G, Moresco JJ, Yates JR 3rd, Ashton R, Schekman R, Tong Y, Audhya A. TFG facilitates outercoat disassembly on COPII transport carriers to promote tethering and fusion with ER-Golgi intermediate compartments. Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):E7707-E7716. doi: 10.1073/pnas.1709120114. Epub 2017 Aug 29. Erratum in: Proc Natl Acad Sci U S A. 2017 Sep 25;:. PubMed PMID: 28851831; PubMed Central PMCID: PMC5604033.