University of Wisconsin–Madison

Michelle Kimple, phd

Assistant Professor, Medicine (Endocrinology, Diabetes & Metabolism)


4148 UW Medical Foundation Centennial Building
1685 Highland Ave

Michelle Kimple

Research Description

Dr. Kimple leads a multi-level research team whose focus is on understanding how the beta-cells of the pancreas respond to nutrient and hormonal stimulation to affect biological changes. Her group is especially interested in elucidating how dysfunctional G protein-coupled receptor signaling pathways contribute to the pathogenesis of type 1 and type 2 diabetes and in translating these insights into new and improved diabetes therapeutics. Dr. Kimple’s research has been funded almost continuously from her PhD onwards by the National Institutes of Health and the Juvenile Diabetes Research Foundation, among other agencies. Her work has been featured in several university press releases and patent applications. Dr. Kimple has been the recipient of several awards, including a Preparing Future Faculty Fellowship from Duke University, where she learned the skills necessary to be a successful mentor and teacher while maintaining a top-tier research laboratory.

Honors & Awards

  • Mentor, American Society for Pharmacology & Experimental Biology (ASPET) Zannoni Summer Undergraduate Research Fellowship
  • Mentor, Hilldale Undergraduate/Faculty Research Fellowship
  • Best Poster Award, Drug Development Category, American Society of Biochemistry and Molecular Biology, Experimental Biology 2012
  • Mentored Research Scientist Development Award, NIH/NIDDK
  • Duke ‘Preparing Future Faculty’ Program Fellowship

Michelle Kimple, PhD, assistant professor, Division of Endocrinology, Department of Medicine, was funded by the American Diabetes Association for her proposal titled “Arachidonic Acid Metabolism and Beta-Cell Dysfunction: Beyond COX-2.” The long-term goal is to fully characterize the PGE2 synthesis and signaling pathways in the normal and diabetic beta-cell, determining steps that become dysfunctional in the diabetic state, and ultimately modulating these steps for preventative and therapeutic purposes.

Selected Publications

(Find further recent publications on PubMed)