University of Wisconsin–Madison

Cynthia J. Koziol-White, Phd

Assistant Professor, Department of Pharmacology, Rutgers University

ckoziolwhite@uwalumni.com

Advisor: Dr. Paul Bertics

Graduation: 07/2009
Research Interest: Examining mechanisms underlying airway inflammation and hyperreactivity in murine models as well as ex vivo human lungs

Cynthia Koziol-White

Publications

  1. Koziol-White C.J., Jia Y., Baltus G.A., Cooper P.R., Zaller D.M., Crackower M.A., Sirkowski E.E., Smock S., Alves S.E., Panettieri R.A., Jr.Inhibition of spleen tyrosine kinase attenuates IgE-mediated bronchoconstriction and mediator release in human precision cut lung slices.  Br J Pharmacol. 2016 Jul 15.
  2. Koziol-White C.J., Yoo E.J., Cao G., Zhang J., Papanikolaou E., Puchkarsky I., Andrews A., Himes B., Damoiseaux RD., Liggett S., Di Carlo D., Kurten R., Panettieri R.A., Jr.:  Inhibition of phosphoinositide 3-kinase (PI3K) promotes bronchodilation of human small airways in a Rho kinase-dependent manner.  Br J Pharmacol. 2016 Jun 28. [Epub ahead of print]
  3. Jude J., Koziol-White C., Scala J., Jester W., Maute C., Dalton P., Panettieri R.A., Jr.:  Formaldehyde induces Rho-associated kinase activity to evoke airway hyperresponsiveness.  Am. J. Respir. Am J Respir Cell Mol Biol. 2016 May 5. [Epub ahead of print]
  4. Li S., Koziol-White C., Jude J., Jiang M., Cao G., Yoo E., Jester W., Morley M.P., Lu M.M., Panettieri R.A., Jr., Morrisey E.E.: An epithelial-smooth muscle paracrine pathway that induces asthma through ectopic expression of neuropeptide-Y.  J. Clin. Invest., 126(5):1978-82. doi: 10.1172/JCI81389. Epub 2016 Apr 18.
  5. Ghosh A., Koziol-White C.J., Asosingh K., Cheng G., Ruple L., Rodgers J., Groneberg D., Friebe A., Comhair S., Stasch J.-P., Panettieri R.A., Jr., Aronica. M.A., Erzurum S.C., Stuehr D.J.:  Soluble guanylate cyclase as an alternative target for bronchodilator therapy in asthma.  PNAS, 113(17):E2355-62.  Epub 2016 Apr 11.
  6. Carr R, Koziol-White C, Zhang J, Lam H, An SS, Tall GG, Panettieri RA, Benovic JL. Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms. Mol Pharmacol. 2015 Oct 13. [Epub ahead of print]
  7. Sun Y, Jain D, Koziol-White CJ, Genoyer E, Gilbert M, Tapia K, Panettieri RA Jr, Hodinka RL, López CB. Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans. PLoS Pathog. 2015 Sep 3; 11(9):e1005122. eCollection 2015 Sep.
  8. Himes BE, Koziol-White C, Johnson M, Nikolos C, Jester W, Klanderman B, Litonjua AA, Tantisira KG, Truskowski K, MacDonald K, Panettieri RA Jr, Weiss ST. Vitamin D Modulates Expression of the Airway Smooth Muscle Transcriptome in Fatal Asthma. PLoS One. 2015 Jul 24; 10(7):e0134057. eCollection 2015.
  9. Kim WK, Jain D, Sanchez MD, Koziol-White CJ, Matthews K, Ge MQ, Haczku A, Panettieri RA Jr, Frieman MB, Lopez CB. Deficiency of MDA5 Results in Exacerbated Chronic Post-Viral Lung Inflammation. Am J Respir Crit Care Med. 2014 Feb 15;189(4):437-48.
  10. Robinett KS, Koziol-White CJ, Akoluk A, An SS, Panettieri Jr RA, Liggett SB. Bitter Taste Receptor Function in Asthmatic and Nonasthmatic Human Airway Smooth Muscle Cells. Am J Respir Cell Mol Biol. 2013 Nov 12.