Naval Shanware, PhD

Position title: Senior Consultant, Navigant, San Francisco Bay Area, CA

Phone: Advisor: Dr. Randal Tibbetts

Address:
Graduation: 12/2009
Research Interest: Regulation of the DNA damage response and circadian rhythms by CK1

Skills & Expertise

Molecular biology, HPLC, Western blotting, protein purification, biochemistry, cell, tissue culture, in vivo, molecular cloning, cell culture, cell biology, protein expression, transfection, drug discovery

Publications

Shanware NP, Bray K, and Abraham R. (2013).The PI3K, metabolic, and autophagy networks: interactive partners in cellular health and disease. Annu Rev Pharmacol Toxicol. 53:89-106. Review. PMID: 23294306 [PubMed – indexed for MEDLINE]
Shanware NP, Mullen AR, DeBerardinis RJ, and Abraham RT (2011).Glutamine: pleiotropic roles in tumor growth and stress resistance. J Mol Med (Berl). 89:229-236. PMID: 21301794
Shanware NP, Hutchinson JA, Kim SH, Zhan L, Bowler MJ, and Tibbetts RS (2011). Casein kinase 1-dependent phosphorylation of familial advanced sleep phase syndrome-associated residues controls PERIOD 2 stability. J Biol Chem. 286:12766-12774. PMCID: PMC3069476
Hutchinson JA, Shanware NP, Chang H, and Tibbetts RS (2011). Regulation of ribosomal protein S6 phosphorylation by casein kinase 1 and protein phosphatase 1. J Biol Chem. 286:8688-8696. PMCID: PMC3048750
Shanware NP, Zhan L, Hutchinson JA, Kim SH, Williams LM, and Tibbetts RS (2010). Conserved and distinct modes of CREB/ATF transcription factor regulation by PP2A/B56gamma and genotoxic stress. PLoS One. 5:e12173. PMCID: PMC2921338
Kim SH, Shanware NP, Bowler MJ, and Tibbetts RS (2010). Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA. J Biol Chem. 285:34097-34105. PMCID: PMC2962508
Shanware NP, Williams LM, Bowler MJ, and Tibbetts RS (2009). Non-specific in vivo inhibition of CK1 by the pyridinyl imidazole p38 inhibitors SB 203580 and SB 202190. BMB Rep. 42:142-147. PMID: 19336000.
Shanware NP, Trinh AT, Williams LM, and Tibbetts RS (2007). Coregulated ataxia telangiectasia-mutated and casein kinase sites modulate cAMP-response element-binding protein-coactivator interactions in response to DNA damage. J Biol Chem. 282:6283-6291. PMID: 17209043