Jay Tan, PhD

Position title: Assistant Professor, Aging Institute of UPMC, Department of Cell Biology, University of Pittsburgh School of Medicine

Email: jay.tan@pitt.edu

Phone: Advisor: Dr. Richard Anderson

Graduation: 06/2015
Research Interest: Phosphoinositide signaling, EGFR, autophagy, cancer metabolism

Jay Tan


  • Choi S, Thapa N, Tan X, Hedman AC, Anderson RA., 2015, “PIP kinases define PI4,5P2 signaling specificity by association with effectors,” Biochim. Biophys. Acta., 1851:711-723. PMCID: PMC4380618
  • Tan X, Sun Y, Thapa N, Liao Y, Hedman AC, Anderson RA., 2015, “LAPTM4B is a PtdIns(4,5)P2 effector that regulates EGFR signaling, lysosomal sorting, and degradation,” EMBO J., 34:475-90. PMCID: PMC4331002
  • Tan X, Thapa N, Sun Y, Anderson RA., 2015, “A kinase independent role for EGF receptor in autophagy initiation,” Cell, 160:145-60. PMCID: PMC4297316
  • Thapa N, Choi S, Hedman A, Tan X, Anderson RA., 2013, “Phosphatidylinositol phosphate 5-kinase Iγi2 in association with Src controls anchorage-independent growth of tumor cells,” J. Biol. Chem., 288:34707-34718. PMCID: PMC3843082
  • Sun Y, Hedman AC, Tan X, and Anderson RA., 2013, “An unexpected role for PI4,5P2 in EGF receptor endosomal trafficking,” Cell Cycle, 12:1991-1992. PMCID: PMC3737296