Zhen Zhang, PhD
Position title: Pharmacologist, FDA, Washington D.C. Area
Email: zhen0806@gmail.com
Phone: Advisor: Dr. Meyer Jackson
Address:
Graduation: 05/2009
Publications
- Zhang Z, Wang D, Sun T, Xu J, Chiang HC, Shin W,Wu LG. The SNARE proteins SNAP25 and synaptobrevin are involved in endocytosis at hippocampal synapses.J Neurosci. 2013 May 22;33(21):9169-75. doi: 10.1523/JNEUROSCI.0301-13.2013. PMID: 23699527 [PubMed – in process]
- Xu J, Luo F, Zhang Z, Xue L, Wu XS, Chiang HC, Shin W,Wu LG.SNARE proteins synaptobrevin, SNAP-25, and syntaxin are involved in rapid and slow endocytosis at synapses.Cell Rep. 2013 May 30;3(5):1414-21. doi: 10.1016/j.celrep.2013.03.010. Epub 2013 May 2. PMID: 23643538 [PubMed – in process]
- Zhang Z, Wu Y, Wang Z, Dunning FM, Rehfuss J, Ramanan D, Chapman ER,Jackson MB.Release mode of large and small dense-core vesicles specified by different synaptotagmin isoforms in PC12 cells.Mol Biol Cell. 2011 Jul 1;22(13):2324-36. PMCID: PMC3128534
- Wang D, Zhang Z, Dong M, Sun S, Chapman ER,Jackson MB.Syntaxin requirement for Ca2+-triggered exocytosis in neurons and endocrine cells demonstrated with an engineered neurotoxin.Biochemistry. 2011 Apr 12;50(14):2711-3. PMCID: PMC3072107
- Wang D, Zhang Z, Chanda B,Jackson MB. Improved probes for hybrid voltage sensor imaging. Biophys J. 2010 Oct 6;99(7):2355-65. PMCID: PMC3042572
- Zhang Z, Hui E, Chapman ER, Jackson MB. Regulation of exocytosis and fusion pores by synaptotagmin-effector interactions. Mol Biol Cell. 2010 Aug 15;21(16):2821-31. PMCID: PMC2921110
- Xue L, Zhang Z, McNeil BD, Luo F, Wu XS, Sheng J, Shin W, and Wu LG. (2012) Voltage-dependent calcium channels at the plasma membrane, but not vesicular channels, couple exocytosis to endocytosis. Cell Rep. 1:632-638. Epub 2012 May 31. PMCID: PMC3401380
- Wang D, McMahon S, Zhang Z, Jackson MB. (2012) Hybrid Voltage Sensor Imaging of Electrical Activity from Neurons in Hippocampal Slices From Transgenic Mice. J Neurophysiol. 2012 Sep 19. [Epub ahead of print] PMID: 22993267
- Zhang Z, and Jackson MB. Membrane bending energy and fusion pore kinetics in Ca2+-triggered exocytosis. Biophys J. 98:2524-2534. PMCID: PMC2877347
- Zhang Z, Hui E, Chapman ER, and Jackson MB. (2009) Phosphatidylserine Regulation of Ca2+-Triggered Exocytosis and Fusion Pores. Mol. Biol Cell. 20:5086-5095.
- Zhang Z and Jackson MB. (2008) Temperature dependence of fusion pore kinetics and fusion pore regulation in Ca2+-triggered exocytosis from PC12 cells. J Gen Physiol. 131:117-124.
- Zhang ZJ, Zhang Z, Jackson MB. Synaptotagmin IV modulation of vesicle size and fusion pores in PC12 cells. Biophys J. 98(6):968-978 (2010)