Raines lab identifies connection between two promising cancer treatment strategies

An important study led by the laboratory of MCP Faculty Member Dr. Ronald Raines was published in the latest issue of ACS Central Science, a journal of the American Chemical Society. The experiment identified Globo H, a well-known human cancer antigen, as a binding site for Human Ribonuclease 1, an enzyme that can kill cells by degrading their RNA. Raines has studied ribonucleases extensively, and by showing that these cytotoxic enzymes bind to the cancer antigen Globo H, which is already being developed as an antigen for a cancer vaccine, the new paper may provide important insight into how to selectively kill cancer cells. Read the full UW News story here, or click here to access the paper.