People Type: Alumni

Biography Experience Results-driven molecular pharmacologist with experience in in vitro and in vivo assay design and execution. Strong background in identifying and characterizing molecular pathways in oncology leading to pathologically diseased states. Well-versed in a wide range of molecular and pharmacological techniques to explore signal transduction and function in cells and animal models. Independent thinker …

Biography Publications Choi S, Thapa N, Tan X, Hedman AC, Anderson RA., 2015, “PIP kinases define PI4,5P2 signaling specificity by association with effectors,” Biochim. Biophys. Acta., 1851:711-723. PMCID: PMC4380618 Tan X, Sun Y, Thapa N, Liao Y, Hedman AC, Anderson RA., 2015, “LAPTM4B is a PtdIns(4,5)P2 effector that regulates EGFR signaling, lysosomal sorting, and degradation,” …

Biography Alumni News Vaccine and Therapeutic Proteins Formulation Research and Development at Merck Post-doctoral Fellow with Stanley Opella, University of California, 2001-2005 Publications Salnikova MS, Davis H, Mensch C, Celano L, and Thiriot DS (2012). Influence of formulation pH and suspension state on freezing-induced agglomeration of aluminum adjuvants. J Pharm Sci. 101:1050-62. Epub 2011 Nov …

Biography Publications Brindikova, TA; Bourcier, N; Torres, B; Pchejetski, D; Gekle, M; Maximov, GV; Montminy, V; Insel, PA; Orlov, SN; and Isenring ,P. (2003) Purinergic-induced signaling in C11-MDCK cells inhibits the secretory Na-K-Cl cotransporter. Am J Physiol Cell Physiol. 285:C1445-1453. Hughes, RJ; Torres, B; Zambon, AC; Arthur, D; Bohmann, C; Rump, LC; and Insel, PA. …

Biography Publications Calkins MJ, Townsend JA, Johnson DA, Johnson JA. Cystamine protects from 3-nitropropionic acid lesioning via induction of nf-e2 related factor 2 mediated transcription. Exp Neurol. 2010 Jul;224(1):307-17. doi: 10.1016/j.expneurol.2010.04.008. Epub 2010 Apr 18. PubMed PMID: 20406637; PubMed Central PMCID: PMC2885467. Calkins MJ, Johnson DA, Townsend JA, Vargas MR, Dowell JA, Williamson TP, Kraft …

Biography Publications Jackson SA, Olufs ZP, Tran KA, Zaidan NZ, Sridharan R. Alternative Routes to Induced Pluripotent Stem Cells Revealed by Reprogramming of the Neural Lineage. Stem Cell Reports. 2016 Mar 8;6(3):302-11. doi: 10.1016/j.stemcr.2016.01.009. Epub 2016 Feb 18. PubMed PMID: 26905202; PubMed Central PMCID: PMC4788781. Tran KA, Jackson SA, Olufs ZP, Zaidan NZ, Leng N, …