University of Wisconsin School of Medicine and Public Health
Lab Website Ricke Lab Biography Research Interests Understanding the role of endocrine disrupting chemicals, phytonutrients, and stromal-epithelial interactions in the development or treatment of urologic diseases (e.g. benign prostatic hyperplasia and prostate cancer). –Evaluation of bisphenol-A in obstructive voiding disorders (RC2 grant, NIEHS) –Role of phthalates and bisphenols in prostate cancer progression –Evaluation of bisphenol-A …
Biography Research Interest Key words: Gene Regulation, Single Cell and Spatially Resolved, Genomic Tools, Neural Circuitry in Health and Disease I have a strong background in the development and application of quantitative techniques and theoretical frameworks directed towards the interrogation of complex biological systems. My graduate training in molecular and cellular biology at Harvard University …
Biography Research Interests Cardiac Arrhythmia Research Every day, sudden cardiac death unexpectedly claims lives because of adverse drug reactions, inherited conditions, and environmental influences. Often, those lost are in their prime – seemingly healthy athletes, children, newborns, or even a developing baby in mother’s womb. Much of the work in the Robertson lab focuses on …
Lab Website Avtar Roopra Lab Biography Research Interests The lab’s over-arching goal is to understand the epigenetic mechanisms behind transcriptional regulation and chromatin structure in mammals. A major focus is the study of mechanisms that regulate the expression of neuronal target genes. We have shown that the transcription factor NRSF recruits a number of chromatin …
Biography Research Interests Targeted therapy resistance in advanced cancer The Sharifi lab is focused on identifying molecular mechanisms of targeted therapy resistance in advanced breast and prostate cancer to develop new and more effective therapies. Our research utilizes translational liquid biopsy based approaches and patient derived models to evaluate dynamic changes in endocrine and oncogene …
Biography Research Interests The Retroviruses cause a variety of cancers and immunodeficiencies throughout the animal kingdom. Our group is interested in the cell biology underlying the assembly and spread of the human immunodeficiency virus type 1 (HIV-1), the etiological agent causing the acquired immunodeficiency syndrome (AIDS), as well as oncoretroviruses such as the murine leukaemia …
Biography Research Interests The research objectives of my laboratory are to investigate the mechanisms that promote energy expenditure during adaptive thermogenesis. Our work focuses on identifying transcriptional regulators of hepatic lipid processing that fuel thermogenesis and discovering lipid signaling pathways that orchestrate multi-organ communication during cold stress. The Simcox laboratory focuses on two unanswered questions: …
Lab Website Sinha Lab Biography Research Interests Visual Processing: From photons to visual circuit function One of the fundamental goals of neuroscience is to understand how information flow through a neural circuit leads to function and ultimately results in meaningful perception and behavior. Barring a few notable exceptions, this relationship between a neural input and …
Biography Research Interests Molecular and cellular mechanisms of human brain development and evolution. The development of the human brain is a long and complex process that is precisely choreographed through tightly regulated transcriptional programs. Proper regulation of these programs is necessary for developing the numerous functionally distinct regions and cell types of the brain. Since …
Biography Research Interests The South lab studies mechanisms of squamous cell carcinoma (SCC) initiation and progression with a view to developing preventative or curative intervention. One approach to achieving this goal is to study rare familial tumor prone disorders that can inform on more common cancer. We currently focus on aggressive SCC occurring in patients …