University of Wisconsin School of Medicine and Public Health
Lab Website Sauer Lab Biography Research Interests Our lab is interested in how intracellular pathogens parasitize host cells and how the host, in turn, recognizes these pathogens and defends against them. We use the bacterium Listeria monocytogenes, a Gram positive foodborne pathogen, as a model organism to address these questions. L. monocytogenes is capable of …
Lab Website Schnapp Lab Twitter @LynnSchnappMD Biography Research Interests Dr. Schnapp’s research broadly focuses on the processes that govern acute lung injury and its resolution. More specifically, she investigates how scar tissue forms during lung injury and diseases that damage lung function, such as idiopathic pulmonary fibrosis. Using unique mouse models to identify cells and …
Biography Research Interests Targeted therapy resistance in advanced cancer The Sharifi lab is focused on identifying molecular mechanisms of targeted therapy resistance in advanced breast and prostate cancer to develop new and more effective therapies. Our research utilizes translational liquid biopsy based approaches and patient derived models to evaluate dynamic changes in endocrine and oncogene …
Lab Website Sheehan Lab Biography Research Interests My laboratory is interested in molecular mechanisms of coagulation and thrombosis, with emphasis on regulation of the coagulation serine proteases, and identification of novel targets for antithrombotic therapy (Figure 1). Currently, the laboratory is focused on regulation of the intrinsic tenase complex (factor IXa-factor VIIIa) (Figure 2). In …
Biography Research Interests Our laboratory studies the molecular and cellular mechanisms that regulate angiogenesis. We are interested in how alterations in normal regulatory mechanisms, under pathological conditions such as ischemia and diabetes, leads to vascular abnormalities and neovascularization. We use the postnatal developing retinal vasculature as a model to study all aspects of vascular development. …
Biography Research Interests The Retroviruses cause a variety of cancers and immunodeficiencies throughout the animal kingdom. Our group is interested in the cell biology underlying the assembly and spread of the human immunodeficiency virus type 1 (HIV-1), the etiological agent causing the acquired immunodeficiency syndrome (AIDS), as well as oncoretroviruses such as the murine leukaemia …
Biography Research Interests The research objectives of my laboratory are to investigate the mechanisms that promote energy expenditure during adaptive thermogenesis. Our work focuses on identifying transcriptional regulators of hepatic lipid processing that fuel thermogenesis and discovering lipid signaling pathways that orchestrate multi-organ communication during cold stress. The Simcox laboratory focuses on two unanswered questions: …
Lab Website Sinha Lab Biography Research Interests Visual Processing: From photons to visual circuit function One of the fundamental goals of neuroscience is to understand how information flow through a neural circuit leads to function and ultimately results in meaningful perception and behavior. Barring a few notable exceptions, this relationship between a neural input and …
Lab Website Skala Lab Biography Research Interests My lab develops new methods to understand and combat cancer using photonics-based technologies. Optical technologies are attractive for clinical translation because these techniques are inexpensive, portable, fast and provide a wealth of information on tissue structure and function. We are particularly interested in developing personalized cancer treatment strategies, …
Lab Website Slukvin Lab Biography Research Interests Hematopoietic development from pluripotent stem cells; de novo generation of hematopoietic stem cells Clinical Interests General Surgical Pathology, Gastrointestinal tract pathology Honors & Awards 2000 – New Investigator Award and Award for Outstanding Research and Poster Presentation 14th Rochester Trophoblast Conference: The placenta: function and pathobiology in the new millennium: …