University of Wisconsin School of Medicine and Public Health
Lab Website Ponik Lab Biography Research Interests My group is interested in understanding the molecular mechanisms underlying breast cancer risk due to breast density. Patients with mammographically dense breast tissue have a four to six-fold increased risk of developing breast carcinomas. In fact, 1/3 of all breast cancer cases are attributed to breast density, making …
Biography Research Interests Humans studies have revealed consistent alterations in the gut microbiomes of patients with cardiometabolic and aging-associated diseases. A major focus of my group is to understand how variations in the gut microbiome modulate the effects of diet and host’s susceptibility to cardiometabolic disease. To address these questions we use a combination of …
Biography Research Interests The Richards Lab focuses on developing novel immunotherapies for high-risk pediatric leukemias including acute myeloid leukemia (AML). The primary focus of the lab is to optimize chimeric antigen receptor (CAR) T cell therapies and other immune effector cells. There are many reasons that CAR T cells have not been successfully implemented in …
Lab Website Ricke Lab Biography Research Interests Understanding the role of endocrine disrupting chemicals, phytonutrients, and stromal-epithelial interactions in the development or treatment of urologic diseases (e.g. benign prostatic hyperplasia and prostate cancer). –Evaluation of bisphenol-A in obstructive voiding disorders (RC2 grant, NIEHS) –Role of phthalates and bisphenols in prostate cancer progression –Evaluation of bisphenol-A …
Biography Research Interest Key words: Gene Regulation, Single Cell and Spatially Resolved, Genomic Tools, Neural Circuitry in Health and Disease I have a strong background in the development and application of quantitative techniques and theoretical frameworks directed towards the interrogation of complex biological systems. My graduate training in molecular and cellular biology at Harvard University …
Biography Research Interests Cardiac Arrhythmia Research Every day, sudden cardiac death unexpectedly claims lives because of adverse drug reactions, inherited conditions, and environmental influences. Often, those lost are in their prime – seemingly healthy athletes, children, newborns, or even a developing baby in mother’s womb. Much of the work in the Robertson lab focuses on …
Lab Website Avtar Roopra Lab Biography Research Interests The lab’s over-arching goal is to understand the epigenetic mechanisms behind transcriptional regulation and chromatin structure in mammals. A major focus is the study of mechanisms that regulate the expression of neuronal target genes. We have shown that the transcription factor NRSF recruits a number of chromatin …
Lab Website Rose Laboratory Biography Research Interests Antimicrobial resistance is now recognized as a top public health threat in critical need of innovation. Our translational research focuses on the pharmacodynamics of antimicrobials in the treatment of complex bacterial infections. We identify novel ways to employ antibiotics in patients to combat antimicrobial resistance development and treatment …
Lab Website Rui Lab Biography Research Interests The major research interest in our laboratory is the mechanisms of the JAK-STAT signaling pathway in lymphomagenesis. We previously studied primary mediastinal and Hodgkin lymphoma, both of which share biological and molecular features. One common genetic change in these two cancers is an amplification of chromosome 9p24 region …
Lab Website Saha Lab Biography Research Interests My interests lie in using human stem cells together with emerging engineering methods in material science and synthetic biology to make smarter therapeutics, model human disease, and advance personalized medicine. Personalized and Regenerative Medicine Biomaterials Engineering Stem Cell Biology Developmental Biology Signal transduction Systems biology Synthetic biology Evolution …