University of Wisconsin School of Medicine and Public Health
Biography Research Program The Brown Lab focuses on exploring the nexus of pluripotent stem cell (PSC) biology and immunology. We are currently investigating the mechanisms underpinning the immune response to autologous and allogeneic PSC-derived cell therapies. Using transplantation immunology and genomics-based strategies, in conjunction with humanized mouse models, our goals are to 1) improve traditional …
Lab Website Bugni Lab Biography Research Interests Tim Bugni’s research interests are marine natural products chemistry, symbiotic microorganisms, drug discovery, metabolomics, and NMR and MS for structure elucidation of novel natural products. Genetically encoded small molecules, natural products, have been a valuable source of therapeutics particularly in the areas of cancer and infectious disease. However, …
Website Division of Pharmacy Professional Development Biography Research Interests Eric’s primary responsibilities are the development, implementation and evaluation of continuing education offerings for individuals in the pharmaceutical industry within the United States.
Biography Research Interests Drug discovery can be a long and expensive process. To accelerate research in the development of new treatments, phenotypic approaches are used to screen compounds at high-throughput and identify promising candidates quickly. Microscopy imaging and Cell Painting have been widely adopted in industry and academia to determine the effects of drugs by …
Biography Research Description Pain is pervasive and devastating. Poorly treated chronic pain is the largest source of disability in America with an estimated economic cost of more than 500 billion dollars per year. Moreover, existing strategies to disrupt pain (e.g. opiates) have well known and highly undesirable effects on reward circuits in the CNS. Better …
Lab Website Chang Lab Biography Research Interests We use various forms of gene targeting in mouse embryonic stem cells to generate genetically engineered mouse lines. One major focus of our lab is to use these mutant mice as animal models for human diseases, which allows us to study the molecular mechanism of diseases in vivo. …
HHMI Investigator HHMI Neuroscience Faculty Page Neuroscience Faculty Page Lab Website Chapman Lab Biography Research Description Our laboratory studies membrane trafficking and fusion in neurons; our over-arching goal is to understand presynaptic aspects of synaptic transmission and plasticity. To address these questions, our laboratory is divided into three related and highly interactive subgroups: Nanomechanics of …
Biography Research Description Over 50% of cancer patients receive radiation therapy as a component of their treatment. My laboratory aims to study how chromosomal Instability (CIN), an ongoing rate of chromosome missegregation events over the course of multiple cell divisions, which is very common in cancer, affects sensitivity to radiation therapy. We aim to discover …
Biography Research Interests Brainstem Circuits for Motor Control In the Cregg Lab, we focus on understanding brainstem circuits and their critical role in motor control. Our team employs cutting-edge techniques to dissect brainstem motor circuits in sophisticated anatomical, molecular, and functional detail. Our work aims to enhance our comprehension of the neural circuitry controlling movement, …
Biography Research Interests Our laboratory focuses on understanding how cells die. We are especially interested in elucidating how abnormalities in cell death contribute to cancer and other diseases and in translating these insights into improved biomarkers and therapies. We are currently exploring the following questions: How do cancer cells exploit the cellular stress response to …